Product Datasheet
PLEKHA1 Antibody
Catalog Number: 47177
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9HB21
NCBI Gene ID:59338
Gene Accssion:BC001136
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human PLEKHA1
- appl_detail:
Immunofluorescence:1: 20-100
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total PLEKHA1 protein.
- Background:
- This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.
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