Product Datasheet
NTRK2 Antibody
Catalog Number: 47171
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q16620
NCBI Gene ID:4915
Gene Accssion:BC031835
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human NTRK2
- appl_detail:
Immunofluorescence:1: 20-100
- other_names:
- TRKB; trk-B; GP145-TrkB
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total NTRK2 protein.
- Background:
- This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.?
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