Product Datasheet
MYOZ2 Antibody
Catalog Number: 47160
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9NPC6
NCBI Gene ID:51778
Gene Accssion:BC017402
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein
- appl_detail:
Immunofluorescence:1: 40-200
- other_names:
- CS-1; CMH16; C4orf5
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total MYOZ2 protein.
- Background:
- The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder.
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