Product Datasheet
MRPL1 Antibody
Catalog Number: 47159
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9BYD6
NCBI Gene ID:65008
Gene Accssion:BC014356
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human MRPL1
- appl_detail:
- Western blotting:1:500-2000
Immunofluorescence:1: 20-100
- other_names:
- L1MT; BM022; MRP-L1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total MRPL1 protein.
- Background:
- Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family.?
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