Product Datasheet
HOXA10 Antibody
Catalog Number: 47136
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P31260
NCBI Gene ID:3206
Gene Accssion:NP_061824
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human HOXA10
- appl_detail:
- Western blotting:1:200-1000
Immunofluorescence:1: 20-100
- other_names:
- PL; HOX1; HOX1H; HOX1.8
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total HOXA10 protein.
- Background:
- In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the downstream homeobox A9 (HOXA9) gene.
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