Product Datasheet  
GNB1L Antibody  
Catalog Number: 47128  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q9BYB4
    NCBI Gene ID:54584
    Gene Accssion:NP_443730
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20C
  • Immunogen:  
  • Synthetic peptide of human GNB1L
  • reactivity:  
  • Hu
  • appl_detail:  

  • Immunofluorescence:1: 20-100
  • other_names:  
  • GY2; FKSG1; WDR14; WDVCF; DGCRK3
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • The antibody detects endogenous levels of total GNB1L protein.
  • Applications:  
  • IHC
  • Background:  
  • This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome. Therefore, this gene may contribute to the etiology of those disorders. Transcripts from this gene share exons with some transcripts from the C22orf29 gene.



 
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