Product Datasheet
GDI2 Antibody
Catalog Number: 47126
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P50395
NCBI Gene ID:2665
Gene Accssion:BC005145
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human GDI2
- appl_detail:
Immunofluorescence:1: 20-100
- other_names:
- RABGDIB; HEL-S-46e
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total GDI2 protein.
- Background:
- GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms.?
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