Product Datasheet
EXO5 Antibody
Catalog Number: 47115
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9H790
NCBI Gene ID:64789
Gene Accssion:BC021969
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human EXO5
- appl_detail:
Immunofluorescence:1: 25-100
- other_names:
- DEM1; Exo V; hExo5; C1orf176
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total EXO5 protein.
- Background:
- The protein encoded by this gene is a single-stranded DNA (ssDNA)-specific exonuclease that can slide along the DNA before cutting it. However, human replication protein A binds ssDNA and restricts sliding of the encoded protein, providing a 5'-directionality to the enzyme. This protein localizes to nuclear repair loci after DNA damage.
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