Product Datasheet
EN1 Antibody
Catalog Number: 47107
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q05925
NCBI Gene ID:2019
Gene Accssion:NP_001417
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human EN1
- appl_detail:
- Western blotting:1:500-2000
Immunofluorescence:1: 20-100
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total EN1 protein.
- Background:
- Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.
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