Product Datasheet  
EIF2S1 Antibody  
Catalog Number: 47097  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P05198
    NCBI Gene ID:1965
    Gene Accssion:NP_004085
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20C
  • Immunogen：  
  • Synthetic peptide of human EIF2S1
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting:1:200-1000
    Immunofluorescence:1: 20-100
  • other_names：  
  • EIF2; EIF-2; EIF2A; EIF-2A; EIF-2alpha
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • The antibody detects endogenous levels of total EIF2S1 protein.
  • Applications：  
  • WB, IHC
  • Background：  
  • The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).



 
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