Product Datasheet
DUS2 Antibody
Catalog Number: 47082
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9NX74
NCBI Gene ID:54920
Gene Accssion:BC006527
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human DUS2
- appl_detail:
- Western blotting:1:200-1000
Immunofluorescence:1: 20-100
- other_names:
- SMM1; DUS2L; URLC8
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total DUS2 protein.
- Background:
- This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene.
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