Product Datasheet
DLEC1 Antibody
Catalog Number: 47059
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9Y238
NCBI Gene ID:9940
Gene Accssion:NP_031361
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human DLEC1
- appl_detail:
Immunofluorescence:1: 20-100
- other_names:
- F56; DLC1; DLC-1; CFAP81
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total DLEC1 protein.
- Background:
- The cytogenetic location of this gene is 3p21.3, and it is located in a region that is commonly deleted in a variety of malignancies. Down-regulation of this gene has been observed in several human cancers including lung, esophageal, renal tumors, and head and neck squamous cell carcinoma. In some cases, reduced expression of this gene in tumor cells is a result of aberrant promoter methylation. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins.
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