Product Datasheet
DDX23 Antibody
Catalog Number: 47038
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9BUQ8
NCBI Gene ID:9416
Gene Accssion:BC002366
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human DDX23
- appl_detail:
Immunofluorescence:1: 20-100
- other_names:
- prp28; PRPF28; U5-100K; SNRNP100; U5-100KD
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total DDX23 protein.
- Background:
- This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined.
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