Product Datasheet
DDOST Antibody
Catalog Number: 47035
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P39656
NCBI Gene ID:1650
Gene Accssion:BC002594
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human DDOST
- appl_detail:
- Western blotting:1:200-1000
Immunofluorescence:1: 25-100
- other_names:
- OST; WBP1; AGER1; CDG1R; OST48; OKSWcl45
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total DDOST protein.
- Background:
- This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.
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