Product Datasheet
CYP26B1 Antibody
Catalog Number: 47001
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9NR63
NCBI Gene ID:56603
Gene Accssion:BC069443
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human CYP26B1
- appl_detail:
Immunofluorescence:1: 20-100
- other_names:
- RHFCA; CYP26A2; P450RAI2; P450RAI-2
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total CYP26B1 protein.
- Background:
- This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants.?
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