Product Datasheet
CPSF3L Antibody
Catalog Number: 46985
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q5TA45
NCBI Gene ID:54973
Gene Accssion:BC013904
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human CPSF3L
- appl_detail:
Immunofluorescence:1: 25-100
- other_names:
- RC68; INT11; RC-68; INTS11; CPSF73L
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total CPSF3L protein.
- Background:
- The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).
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