Product Datasheet
EOGT Antibody
Catalog Number: 47623
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q5NDL2
NCBI Gene ID:285203
Gene Accssion:NP_001265618
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human EOGT
- appl_detail:
- IHC dilution:1: 10-50
- other_names:
- AOS4; AER61; EOGT1; C3orf64
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total EOGT protein.
- Background:
- This gene encodes an enzyme that acts in the lumen of the endoplasmic reticulum to catalyze the transfer of N-acetylglucosamine to serine or threonine residues of extracellular-targeted proteins. This enzyme modifies proteins containing eukaryotic growth factor (EGF)-like domains, including the Notch receptor, thereby regulating developmental signalling. Mutations in this gene have been observed in individuals with Adams-Oliver syndrome 4. Alternative splicing results in multiple transcript variants.
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