Product Datasheet
ZNF85 Antibody
Catalog Number: 47620
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q03923
NCBI Gene ID:7639
Gene Accssion:NP_003420
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human ZNF85
- appl_detail:
- WB dilution:1:500-2000
IHC dilution:1: 20-100
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total ZNF85 protein.
- Background:
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF85 (Zinc finger protein 85), also known as zinc finger protein HPF4 or HTF1, is a member of the ZNF91 family and is thought to be involved in transcriptional regulation. ZNF85 is highly expressed in testicular tissue and localizes to the nucleus. ZNF85 contains sixteen C2H2-type zinc fingers and one KRAB domain through which it is thought to be involved in DNA-binding and transcriptional regulation.
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