Product Datasheet
CNR1 Antibody
Catalog Number: 46963
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P21554
NCBI Gene ID:1268
Gene Accssion:NP_001153698
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human CNR1
- appl_detail:
Immunofluorescence:1: 20-100
- other_names:
- CB1; CNR; CB-R; CB1A; CB1R; CANN6; CB1K5
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total CNR1 protein.
- Background:
- This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
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