Product Datasheet
ACD Antibody
Catalog Number: 46923
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q96AP0
NCBI Gene ID:65057
Gene Accssion:NP_001075955
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human ACD
- appl_detail:
Immunofluorescence:1: 20-100
- other_names:
- PIP1; PTOP; TPP1; TINT1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total ACD protein.
- Background:
- This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.
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