Product Datasheet
UTP4 Antibody
Catalog Number: 46703
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q969X6
NCBI Gene ID:84916
NCBI Protein:BC009348
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic protein corresponding to residues near the C terminal of human UTP4
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 20-100
- other_names:
- NAIC; CIRH1A; CIRHIN; TEX292
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total UTP4 protein.
- Background:
- This gene encodes a WD40-repeat-containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence. Alternative splicing results in multiple transcript variants.
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