Product Datasheet  
UTP18 Antibody  
Catalog Number: 46702  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q9Y5J1
    NCBI Gene ID:51096
    NCBI Protein:NP_057085
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to residues near the C terminal of human UTP18
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1: 10-50
  • other_names：  
  • WDR50; CGI-48
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • The antibody detects endogenous levels of total UTP18 protein.
  • Applications：  
  • IHC
  • Background：  
  • WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. UTP18 (U3 small nucleolar RNA-associated protein 18), also known as WDR50 (WD repeat-containing protein 50), is a 556 amino acid protein that localizes to the nucleus, contains six WD repeats and is thought to be involved in the processing of pre-18S ribosomal RNA. The gene encoding UTP18 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.



 
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