Product Datasheet
TIMM21 Antibody
Catalog Number: 46685
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9BVV7
NCBI Gene ID:29090
NCBI Protein:BC000892
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic protein corresponding to residues near the C terminal of human TIMM21
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 20-100
- other_names:
- TIM21; HSPC154; C18orf55
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total TIMM21 protein.
- Background:
- Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex. TIM21 probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.
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