Product Datasheet
PRRX1 Antibody
Catalog Number: 46650
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P54821
NCBI Gene ID:5396
NCBI Protein:NP_073207
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human PRRX1
- appl_detail:
Immunohistochemistry: 1: 20-100
- other_names:
- PMX1; PRX1; AGOTC; PHOX1; PRX-1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total PRRX1 protein.
- Background:
- The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns.
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