Product Datasheet
MTNR1B Antibody
Catalog Number: 46617
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P49286
NCBI Gene ID:4544
NCBI Protein:NP_005950
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human MTNR1B
- appl_detail:
Immunohistochemistry: 1: 30-150
- other_names:
- MT2; FGQTL2; MEL-1B-R
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total MTNR1B protein.
- Background:
- This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.?
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