Product Datasheet  
MEIOB Antibody  
Catalog Number: 46611  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q8N635
    NCBI Gene ID:254528
    NCBI Protein:BC029829
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic protein corresponding to residues near the C terminal of human MEIOB
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1: 25-100
  • other_names：  
  • gs129; C16orf73
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • The antibody detects endogenous levels of total MEIOB protein.
  • Applications：  
  • IHC
  • Background：  
  • Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro (By similarity).



 
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