Product Datasheet
MARK2 Antibody
Catalog Number: 46607
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q7KZI7
NCBI Gene ID:2011
NCBI Protein:NP_001034558
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to internal residues of human MARK2
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1: 25-100
- other_names:
- EMK1; EMK-1; PAR-1; Par1b; Par-1b
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total MARK2 protein.
- Background:
- This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene.
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