Product Datasheet
LPL Antibody
Catalog Number: 46599
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P06858
NCBI Gene ID:4023
NCBI Protein:NP_000228
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human LPL
- appl_detail:
Immunohistochemistry: 1: 25-100
- other_names:
- LIPD; HDLCQ11
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total LPL protein.
- Background:
- LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.?
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