Product Datasheet
HSF4 Antibody
Catalog Number: 46581
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9ULV5
NCBI Gene ID:3299
NCBI Protein:NP_001529
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to internal residues of human HSF4
- appl_detail:
Immunohistochemistry: 1: 40-200
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total HSF4 protein.
- Background:
- Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.?
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