Product Datasheet
HOXA7 Antibody
Catalog Number: 46578
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P31268
NCBI Gene ID:3204
NCBI Protein:NP_008827
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to internal residues of human HOXA7
- appl_detail:
Immunohistochemistry: 1: 50-300
- other_names:
- ANTP; HOX1; HOX1A; HOX1.1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total HOXA7 protein.
- Background:
- In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila.?
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