Product Datasheet
HIST1H1C Antibody
Catalog Number: 46576
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P16403
NCBI Gene ID:3006
NCBI Protein:BC002649
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein of human HIST1H1C
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- H1C; H1.2; H1F2; H1s-1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total HIST1H1C protein.
- Background:
- Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
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