Product Datasheet
CORO2A Antibody
Catalog Number: 46538
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q92828
NCBI Gene ID:7464
NCBI Protein:NP_003380
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to internal residues of human CORO2A
- appl_detail:
Immunohistochemistry: 1: 30-150
- other_names:
- IR10; WDR2; CLIPINB
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total CORO2A protein.
- Background:
- This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants.
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