Product Datasheet
COL11A1 Antibody
Catalog Number: 46531
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P12107
NCBI Gene ID:1301
NCBI Protein:BC117697
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic protein corresponding to internal residues of human COL11A1
- appl_detail:
Immunohistochemistry: 1: 25-100
- other_names:
- STL2; COLL6; CO11A1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total COL11A1 protein.
- Background:
- This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene.
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