Product Datasheet
CLCNKA Antibody
Catalog Number: 46512
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P51800
NCBI Gene ID:1187
NCBI Protein:NP_004061
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human CLCNKA
- appl_detail:
Immunohistochemistry: 1: 20-100
- other_names:
- CLCK1; ClC-K1; hClC-Ka
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total CLCNKA protein.
- Background:
- This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
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