Product Datasheet
CHST11 Antibody
Catalog Number: 46498
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9NPF2
NCBI Gene ID:50515
NCBI Protein:BC013315
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic protein corresponding to residues near the C terminal of human CHST11
- appl_detail:
Immunohistochemistry: 1: 25-100
- other_names:
- C4ST; C4ST1; C4ST-1; HSA269537
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total CHST11 protein.
- Background:
- The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving this gene and IgH, t(12;14)(q23;q32), has been reported in a patient with B-cell chronic lymphocytic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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