Product Datasheet
CHRNA6 Antibody
Catalog Number: 46496
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q15825
NCBI Gene ID:8973
NCBI Protein:NP_004189
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human CHRNA6
- appl_detail:
Immunohistochemistry: 1: 25-100
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total CHRNA6 protein.
- Background:
- This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence.?
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