Product Datasheet
CDH17 Antibody
Catalog Number: 46450
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q12864
NCBI Gene ID:1015
NCBI Protein:NP_004054
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human CDH17
- appl_detail:
Immunohistochemistry: 1: 25-100
- other_names:
- HPT1; CDH16; HPT-1
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total CDH17 protein.
- Background:
- This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.?
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