Product Datasheet
C12orf10 Antibody
Catalog Number: 46360
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9HB07
NCBI Gene ID:60314
NCBI Protein:BC028904
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic protein corresponding to residues near the C terminal of human C12orf10
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1: 25-100
- other_names:
- MYG; MYG1; Gamm1; MST024; MSTP024
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total C12orf10 protein.
- Background:
- C12orf10, also known as MYG1, MYG1 is a 376 amino acid nucleo-mitochondrial protein belonging to the UPF0160 (MYG1) family. MYG1 is encoded by a gene that maps to human chromosome 12q13.13 and is ubiquitously expressed in simple as well as complex eukaryotes, with highest levels in testis. Considered to have a metal-dependent protein hydrolase (UPF0160) domain, MYG1 exhibits a mitochondrial targeting signal in the N-terminal region and a Pat7-type nuclear localization signal in the region between amino acids 33-39. Although MYG1 displays differential patterns and levels of expression during embryonic development, expression in normal adult tissues is stable, suggesting MYG1 involvement in early developmental processes and in adult stress/illness conditions. Elevation of MYG1 expression may be also associated with vitiligo susceptibility.
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