Product Datasheet
ATRIP Antibody
Catalog Number: 46323
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q8WXE1
NCBI Gene ID:84126
NCBI Protein:BC030597
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic protein corresponding to residues near the C terminal of human ATRIP
- appl_detail:
Immunohistochemistry: 1: 30-150
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total ATRIP protein.
- Background:
- This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.
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