Product Datasheet
CENPT Antibody
Catalog Number: 46472
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q96BT3
NCBI Gene ID:80152
NCBI Protein:NP_079358
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human CENPT
- appl_detail:
Immunohistochemistry: 1: 25-100
- other_names:
- CENP-T; C16orf56
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total CENPT protein.
- Background:
- The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPT is an additional factor required for centromere assembly (Foltz et al., 2006.
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