Product Datasheet  
UBAC2 Antibody  
Catalog Number: 43984  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q8NBM4
    NCBI Gene ID: 337867
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide of human UBAC2
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Western blotting: 1:200-1000
    Immunohistochemistry: 1: 30-150
  • other_names：  
  • PHGDHL1
  • Purification：  
  • Antigen affinity purification
  • Specificity：  
  • The antibody detects endogenous levels of total UBAC2 protein.
  • Applications：  
  • IHC WB
  • Background：  
  • UBAC2 (ubiquitin-associated domain-containing protein 2), also known as PHGDHL1 (phosphoglycerate dehydrogenase-like protein 1), is a 344 amino acid multi-pass membrane protein that contains one UBA domain and is expressed as multiple alternatively spliced isoforms. The gene encoding UBAC2 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.



 
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