Product Datasheet
EPX Antibody
Catalog Number: 43959
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P11678
NCBI Gene ID: 8288
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human EPX
- appl_detail:
Immunohistochemistry: 1: 20-100
- other_names:
- EPO; EPP; EPXD; EPX-PEN
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total EPX protein.
- Background:
- This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded precursor protein is processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a cluster of three peroxidase genes at chromosome 17q23. Mutations in this gene result in eosinophil peroxidase deficiency.
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