Product Datasheet
DOK2 Antibody
Catalog Number: 43939
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O60496
NCBI Gene ID: 9046
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human DOK2
- appl_detail:
Immunohistochemistry: 1: 20-100
- other_names:
- p56DOK; p56dok-2
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total DOK2 protein.
- Background:
- The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.
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