Product Datasheet
GLI1 Antibody
Catalog Number: 43926
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P08151
NCBI Gene ID: 2735
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human GLI1
- appl_detail:
- Western blotting: 1:200-1000
Immunohistochemistry: 1: 20-100
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total GLI1 protein.
- Background:
- This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.
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