Product Datasheet
PIF1 Antibody
Catalog Number: 43903
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9H611
NCBI Gene ID: 80119
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human PIF1
- appl_detail:
Immunohistochemistry: 1: 20-100
- other_names:
- PIF; C15orf20
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total PIF1 protein.
- Background:
- This gene encodes a DNA-dependent adenosine triphosphate (ATP)-metabolizing enzyme that functions as a 5' to 3' DNA helicase. The encoded protein can resolve G-quadruplex structures and RNA-DNA hybrids at the ends of chromosomes. It also prevents telomere elongation by inhibiting the actions of telomerase. Alternative splicing and the use of alternative start codons results in multiple isoforms that are differentially localized to either the mitochondria or the nucleus.
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