Product Datasheet  
DLK1 Antibody  
Catalog Number: 43875  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: P80370
    NCBI Gene ID: 8788
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Fusion protein of human DLK1
  • reactivity:  
  • Hu
  • appl_detail:  
  • Western blotting: 1:200-1000
    Immunohistochemistry: 1: 20-100
  • other_names:  
  • DLK; FA1; ZOG; pG2; DLK-1; PREF1; Delta1; Pref-1
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • The antibody detects endogenous levels of total DLK1 protein.
  • Applications:  
  • IHC WB
  • Background:  
  • This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal.



 
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