Product Datasheet
BRSK2 Antibody
Catalog Number: 43854
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8IWQ3
NCBI Gene ID: 9024
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human BRSK2
- appl_detail:
Immunohistochemistry: 1: 100-200
- other_names:
- SAD1; SADA; STK29; PEN11B; C11orf7
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total BRSK2 protein.
- Background:
- BRSK2 (BR serine/threonine kinase 2), also known as SAD1, STK29 or PEN11B, is a 736 amino acid protein that contains one protein kinase domain and is preferentially expressed in brain and testis. One of several members of the Ser/Thr protein kinase family, BRSK2 uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be involved in microtubule assembly, neuronal polarization and synaptic development. Additionally, BRSK2 may function as an autoantigen involved in small-cell lung cancer-associated limbic encephalitis. Five isoforms of BRSK2 exist due to alternative splicing events.
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