Product Datasheet
BMP4 Antibody
Catalog Number: 43852
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P12644
NCBI Gene ID: 652
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human BMP4
- appl_detail:
- Western blotting: 1:200-1000
Immunohistochemistry: 1: 20-100
- other_names:
- ZYME; BMP2B; OFC11; BMP2B1; MCOPS6
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total BMP4 protein.
- Background:
- This gene encodes a member of the bone morphogenetic protein (BMP) family of proteins, which is part of the transforming growth factor-beta (TGF-beta) superfamily. Members of the BMP family play an important role in bone and cartilage development. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. Alternative splicing results in multiple transcript variants.
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