Product Datasheet
VPREB1 Antibody
Catalog Number: 43823
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P12018
NCBI Gene ID: 7441
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human VPREB1
- appl_detail:
Immunohistochemistry: 1: 20-100
- other_names:
- IGI; IGVPB; VPREB; CD179a
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total VPREB1 protein.
- Background:
- The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants.?
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