Product Datasheet
PIK3CA Antibody
Catalog Number: 43766
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P42336
NCBI Gene ID: 5290
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human PIK3CA
- appl_detail:
Immunohistochemistry: 1: 20-100
- other_names:
- MCM; CWS5; MCAP; PI3K; CLOVE; MCMTC; p110-alpha
- Purification:
- Antigen affinity purification
- Specificity:
- The antibody detects endogenous levels of total PIK3CA protein.
- Background:
- Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
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